NuRD-mediated deacetylation of H3K27 facilitates recruitment of Polycomb Repressive Complex 2 to direct gene repression

Pluripotent cells possess the ability to differentiate into any cell type. Commitment to differentiate into specific lineages requires strict control of gene expression to coordinate the downregulation of lineage inappropriate genes while enabling the expression of lineage-specific genes. The nucleo...

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Detalles Bibliográficos
Autores principales: Reynolds, Nicola, Salmon-Divon, Mali, Dvinge, Heidi, Hynes-Allen, Antony, Balasooriya, Gayan, Leaford, Donna, Behrens, Axel, Bertone, Paul, Hendrich, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273378/
https://www.ncbi.nlm.nih.gov/pubmed/22139358
http://dx.doi.org/10.1038/emboj.2011.431

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