Loss of Activity-Induced Phosphorylation of MeCP2 Enhances Synaptogenesis, LTP, and Spatial Memory

DNA methylation-dependent epigenetic mechanisms underlie the development and function of the mammalian brain. MeCP2 expresses highly in neurons, and functions as a molecular linker between DNA methylation, chromatin remodeling and transcription regulation. Previous in vitro studies showed neuronal a...

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Detalles Bibliográficos
Autores principales: Li, Hongda, Zhong, Xiaofen, Chau, Kevin Fongching, Williams, Emily Cunningham, Chang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273496/
https://www.ncbi.nlm.nih.gov/pubmed/21765426
http://dx.doi.org/10.1038/nn.2866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273496/
https://www.ncbi.nlm.nih.gov/pubmed/21765426
http://dx.doi.org/10.1038/nn.2866

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