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Aging over 70 Years Is Not a Decisively Dismal Prognostic Factor in Gastric Cancer Surgery

PURPOSE: Gastric cancer has a high incidence and mortality rate in Korea. Despite a growing older population and an increase in the number of older patients with gastric cancer, the older patients are not willing to undergo surgery due to their operative risks. Hence, to determine the clinical chara...

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Autores principales: Cho, Sung-Il, Jang, You-Jin, Kim, Jong-Han, Park, Sung-Soo, Park, Seong-Heum, Kim, Seung-Joo, Kim, Chong-Suk, Mok, Young-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Gastric Cancer Association 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273689/
https://www.ncbi.nlm.nih.gov/pubmed/22324010
http://dx.doi.org/10.5230/jgc.2011.11.4.200
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author Cho, Sung-Il
Jang, You-Jin
Kim, Jong-Han
Park, Sung-Soo
Park, Seong-Heum
Kim, Seung-Joo
Kim, Chong-Suk
Mok, Young-Jae
author_facet Cho, Sung-Il
Jang, You-Jin
Kim, Jong-Han
Park, Sung-Soo
Park, Seong-Heum
Kim, Seung-Joo
Kim, Chong-Suk
Mok, Young-Jae
author_sort Cho, Sung-Il
collection PubMed
description PURPOSE: Gastric cancer has a high incidence and mortality rate in Korea. Despite a growing older population and an increase in the number of older patients with gastric cancer, the older patients are not willing to undergo surgery due to their operative risks. Hence, to determine the clinical characteristics and outcomes of gastric cancer surgery for them, we investigate factors influencing the treatment decision. MATERIALS AND METHODS: Between January 1996 and December 2005, a total of 1,519 patients were classified into two groups; the younger age group between 41 and 69 years of age, and the older age group of 70 years or older. The analysis conducted included patient characteristics, accompanying disorders, related American Society of Anesthesiologists (ASA) grade, pathological characteristics and survival rate for each age group. RESULTS: Significant differences were found in the ASA grade (P<0.001) and the number of accompanying disorders (P<0.001) between the two groups. The average length of hospital stay after surgery was 14.5 days in the younger age group, and 13.3 days in the older age group (P=0.065). The average survival time was 47.5 months in the younger age group, and 43.2 months in the older age group (P<0.001). CONCLUSIONS: This study demonstrated that there was more number of accompanying disorders with a high surgical risk in the older age group. However, there was no significant difference between the older and younger age groups in terms of the incidence of complications, under the given disease conditions and if proper management was provided.
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spelling pubmed-32736892012-02-09 Aging over 70 Years Is Not a Decisively Dismal Prognostic Factor in Gastric Cancer Surgery Cho, Sung-Il Jang, You-Jin Kim, Jong-Han Park, Sung-Soo Park, Seong-Heum Kim, Seung-Joo Kim, Chong-Suk Mok, Young-Jae J Gastric Cancer Original Article PURPOSE: Gastric cancer has a high incidence and mortality rate in Korea. Despite a growing older population and an increase in the number of older patients with gastric cancer, the older patients are not willing to undergo surgery due to their operative risks. Hence, to determine the clinical characteristics and outcomes of gastric cancer surgery for them, we investigate factors influencing the treatment decision. MATERIALS AND METHODS: Between January 1996 and December 2005, a total of 1,519 patients were classified into two groups; the younger age group between 41 and 69 years of age, and the older age group of 70 years or older. The analysis conducted included patient characteristics, accompanying disorders, related American Society of Anesthesiologists (ASA) grade, pathological characteristics and survival rate for each age group. RESULTS: Significant differences were found in the ASA grade (P<0.001) and the number of accompanying disorders (P<0.001) between the two groups. The average length of hospital stay after surgery was 14.5 days in the younger age group, and 13.3 days in the older age group (P=0.065). The average survival time was 47.5 months in the younger age group, and 43.2 months in the older age group (P<0.001). CONCLUSIONS: This study demonstrated that there was more number of accompanying disorders with a high surgical risk in the older age group. However, there was no significant difference between the older and younger age groups in terms of the incidence of complications, under the given disease conditions and if proper management was provided. The Korean Gastric Cancer Association 2011-12 2011-12-29 /pmc/articles/PMC3273689/ /pubmed/22324010 http://dx.doi.org/10.5230/jgc.2011.11.4.200 Text en Copyright © 2011 by The Korean Gastric Cancer Association http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Cho, Sung-Il
Jang, You-Jin
Kim, Jong-Han
Park, Sung-Soo
Park, Seong-Heum
Kim, Seung-Joo
Kim, Chong-Suk
Mok, Young-Jae
Aging over 70 Years Is Not a Decisively Dismal Prognostic Factor in Gastric Cancer Surgery
title Aging over 70 Years Is Not a Decisively Dismal Prognostic Factor in Gastric Cancer Surgery
title_full Aging over 70 Years Is Not a Decisively Dismal Prognostic Factor in Gastric Cancer Surgery
title_fullStr Aging over 70 Years Is Not a Decisively Dismal Prognostic Factor in Gastric Cancer Surgery
title_full_unstemmed Aging over 70 Years Is Not a Decisively Dismal Prognostic Factor in Gastric Cancer Surgery
title_short Aging over 70 Years Is Not a Decisively Dismal Prognostic Factor in Gastric Cancer Surgery
title_sort aging over 70 years is not a decisively dismal prognostic factor in gastric cancer surgery
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273689/
https://www.ncbi.nlm.nih.gov/pubmed/22324010
http://dx.doi.org/10.5230/jgc.2011.11.4.200
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