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Telomerase-Independent Paths to Immortality in Predictable Cancer Subtypes

The vast majority of cancers commandeer the activity of telomerase - the remarkable enzyme responsible for prolonging cellular lifespan by maintaining the length of telomeres at the ends of chromosomes. Telomerase is only normally active in embryonic and highly proliferative somatic cells. Thus, tar...

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Detalles Bibliográficos
Autor principal: Durant, Stephen T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273709/
https://www.ncbi.nlm.nih.gov/pubmed/22315652
http://dx.doi.org/10.7150/jca.3965