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Expanding the action of duplex RNAs into the nucleus: redirecting alternative splicing

Double-stranded RNAs are powerful agents for silencing gene expression in the cytoplasm of mammalian cells. The potential for duplex RNAs to control expression in the nucleus has received less attention. Here, we investigate the ability of small RNAs to redirect splicing. We identify RNAs targeting...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Hu, Jiaxin, Corey, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273794/
https://www.ncbi.nlm.nih.gov/pubmed/21948593
http://dx.doi.org/10.1093/nar/gkr780