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The interaction of Pcf11 and Clp1 is needed for mRNA 3′-end formation and is modulated by amino acids in the ATP-binding site
Polyadenylation of eukaryotic mRNAs contributes to stability, transport and translation, and is catalyzed by a large complex of conserved proteins. The Pcf11 subunit of the yeast CF IA factor functions as a scaffold for the processing machinery during the termination and polyadenylation of transcrip...
Autores principales: | Ghazy, Mohamed A., Gordon, James M. B., Lee, Susan D., Singh, Badri Nath, Bohm, Andrew, Hampsey, Michael, Moore, Claire |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273803/ https://www.ncbi.nlm.nih.gov/pubmed/21993299 http://dx.doi.org/10.1093/nar/gkr801 |
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