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Overcoming natural replication barriers: differential helicase requirements

DNA sequences that form secondary structures or bind protein complexes are known barriers to replication and potential inducers of genome instability. In order to determine which helicases facilitate DNA replication across these barriers, we analyzed fork progression through them in wild-type and mu...

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Detalles Bibliográficos
Autores principales: Anand, Ranjith P., Shah, Kartik A., Niu, Hengyao, Sung, Patrick, Mirkin, Sergei M., Freudenreich, Catherine H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273818/
https://www.ncbi.nlm.nih.gov/pubmed/21984413
http://dx.doi.org/10.1093/nar/gkr836

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