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Phosphorylation of SRSF1 is modulated by replicational stress
DNA ligase I-deficient 46BR.1G1 cells show a delay in the maturation of replicative intermediates resulting in the accumulation of single- and double-stranded DNA breaks. As a consequence the ataxia telangiectasia mutated protein kinase (ATM) is constitutively phosphorylated at a basal level. Here,...
Autores principales: | Leva, Valentina, Giuliano, Serena, Bardoni, Anna, Camerini, Serena, Crescenzi, Marco, Lisa, Antonella, Biamonti, Giuseppe, Montecucco, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273819/ https://www.ncbi.nlm.nih.gov/pubmed/21984412 http://dx.doi.org/10.1093/nar/gkr837 |
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