Characterization of the 6-methyl isoxanthopterin (6-MI) base analog dimer, a spectroscopic probe for monitoring guanine base conformations at specific sites in nucleic acids

We here characterize local conformations of site-specifically placed pairs of guanine (G) residues in RNA and DNA, using 6-methyl isoxanthopterin (6-MI) as a conformational probe. 6-MI is a base analog of G and spectroscopic signals obtained from pairs of adjacent 6-MI residues reflect base–base int...

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Detalles Bibliográficos
Autores principales: Datta, Kausiki, Johnson, Neil P., Villani, Giuseppe, Marcus, Andrew H., von Hippel, Peter H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273825/
https://www.ncbi.nlm.nih.gov/pubmed/22009678
http://dx.doi.org/10.1093/nar/gkr858

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