Relationship of spindle assembly checkpoint fidelity to species body mass, lifespan, and developmental rate

We have examined the tolerance of the spindle assembly checkpoint (SAC), as measured by the appearance of tetraploid cells in the presence of a microtubule inhibitor, in a series of primary cell strains derived from species with diverse lifespan and body size. We find that the integrity of the SAC v...

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Detalles Bibliográficos
Autores principales: Lorenzini, Antonello, Fink, Lauren S., Stamato, Thomas, Torres, Claudio, Sell, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3273901/
https://www.ncbi.nlm.nih.gov/pubmed/22201071

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