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Therapeutic Vaccination With Recombinant Adenovirus Reduces Splenic Parasite Burden in Experimental Visceral Leishmaniasis

Therapeutic vaccines, when used alone or in combination therapy with antileishmanial drugs, may have an important place in the control of a variety of forms of human leishmaniasis. Here, we describe the development of an adenovirus-based vaccine (Ad5-KH) comprising a synthetic haspb gene linked to a...

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Detalles Bibliográficos
Autores principales: Maroof, Asher, Brown, Najmeeyah, Smith, Barbara, Hodgkinson, Michael R., Maxwell, Alice, Losch, Florian O., Fritz, Ulrike, Walden, Peter, Lacey, Charles N. J., Smith, Deborah F., Aebischer, Toni, Kaye, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274377/
https://www.ncbi.nlm.nih.gov/pubmed/22301630
http://dx.doi.org/10.1093/infdis/jir842