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Placental malaria is associated with attenuated CD4 T-cell responses to tuberculin PPD 12 months after BCG vaccination

BACKGROUND: Placental malaria (PM) is associated with prenatal malaise, but many PM+ infants are born without symptoms. As malaria has powerful immunomodulatory effects, we tested the hypothesis that PM predicts reduced T-cell responses to vaccine challenge. METHODS: We recruited healthy PM+ and PM-...

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Detalles Bibliográficos
Autores principales:	Walther, Brigitte, Miles, David JC, Waight, Pauline, Palmero, Melba S, Ojuola, Olubukola, Touray, Ebrima S, Whittle, Hilton, van der Sande, Marianne, Crozier, Sarah, Flanagan, Katie L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274427/ https://www.ncbi.nlm.nih.gov/pubmed/22243970 http://dx.doi.org/10.1186/1471-2334-12-6

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