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Induction of cell proliferation and survival genes by estradiol-repressed microRNAs in breast cancer cells

BACKGROUND: In estrogen responsive MCF-7 cells, estradiol (E(2)) binding to ERα leads to transcriptional regulation of genes involved in the control of cell proliferation and survival. MicroRNAs (miRNAs) have emerged as key post-transcriptional regulators of gene expression. The aim of this study wa...

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Detalles Bibliográficos
Autores principales:	Yu, Xinfeng, Zhang, Xuemei, Dhakal, Ishwori B, Beggs, Marjorie, Kadlubar, Susan, Luo, Dali
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274428/ https://www.ncbi.nlm.nih.gov/pubmed/22260523 http://dx.doi.org/10.1186/1471-2407-12-29

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