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R-848 triggers the expression of TLR7/8 and suppresses HIV replication in monocytes

BACKGROUND: Toll-like receptors (TLR) 7 and 8 are important in single-stranded viral RNA recognition and may play a role in HIV infection and disease progression. We analyzed TLR7/8 expression and signaling in monocytes from HIV-infected and uninfected subjects to investigate a pathway with new pote...

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Detalles Bibliográficos
Autores principales:	Nian, Hua, Geng, Wen-Qing, Cui, Hua-Lu, Bao, Ming-jia, Zhang, Zi-ning, Zhang, Min, Pan, Ying, Hu, Qing-Hai, Shang, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274444/ https://www.ncbi.nlm.nih.gov/pubmed/22243920 http://dx.doi.org/10.1186/1471-2334-12-5

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