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Interaction between Mouse Adenovirus Type 1 and Cell Surface Heparan Sulfate Proteoglycans
Application of human adenovirus type 5 (Ad5) derived vectors for cancer gene therapy has been limited by the poor cell surface expression, on some tumor cell types, of the primary Ad5 receptor, the coxsackie-adenovirus-receptor (CAR), as well as the accumulation of Ad5 in the liver following interac...
Autores principales: | Lenaerts, Liesbeth, van Dam, Wim, Persoons, Leentje, Naesens, Lieve |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274534/ https://www.ncbi.nlm.nih.gov/pubmed/22347482 http://dx.doi.org/10.1371/journal.pone.0031454 |
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