Caffeic Acid Phenethyl Ester Causes p21(Cip1) Induction, Akt Signaling Reduction, and Growth Inhibition in PC-3 Human Prostate Cancer Cells

Caffeic acid phenethyl ester (CAPE) treatment suppressed proliferation, colony formation, and cell cycle progression in PC-3 human prostate cancer cells. CAPE decreased protein expression of cyclin D1, cyclin E, SKP2, c-Myc, Akt1, Akt2, Akt3, total Akt, mTOR, Bcl-2, Rb, as well as phosphorylation of...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Hui-Ping, Jiang, Shih Sheng, Chuu, Chih-Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274546/
https://www.ncbi.nlm.nih.gov/pubmed/22347457
http://dx.doi.org/10.1371/journal.pone.0031286

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274546/
https://www.ncbi.nlm.nih.gov/pubmed/22347457
http://dx.doi.org/10.1371/journal.pone.0031286

Ejemplares similares