Cargando…

Prostaglandin E(2) promotes intestinal tumor growth via DNA methylation

Although DNA methylation is one of the critical ways for silencing tumor suppressor and DNA repair genes during tumor initiation and progression, the mechanisms underlying DNA methylation in cancer remain unclear. Here we show that prostaglandin E(2) (PGE(2)) silences certain tumor suppressor and DN...

Descripción completa

Detalles Bibliográficos
Autores principales: Xia, Dianren, Wang, Dingzhi, Kim, Sun-Hee, Katoh, Hiroshi, DuBois, Raymond N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274627/
https://www.ncbi.nlm.nih.gov/pubmed/22270723
http://dx.doi.org/10.1038/nm.2608