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Prostaglandin E(2) promotes intestinal tumor growth via DNA methylation
Although DNA methylation is one of the critical ways for silencing tumor suppressor and DNA repair genes during tumor initiation and progression, the mechanisms underlying DNA methylation in cancer remain unclear. Here we show that prostaglandin E(2) (PGE(2)) silences certain tumor suppressor and DN...
Autores principales: | Xia, Dianren, Wang, Dingzhi, Kim, Sun-Hee, Katoh, Hiroshi, DuBois, Raymond N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274627/ https://www.ncbi.nlm.nih.gov/pubmed/22270723 http://dx.doi.org/10.1038/nm.2608 |
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