2′-Hy­droxy­methyl-1′-(4-methyl­phen­yl)-2′-nitro-1′,2′,5′,6′,7′,7a′-hexa­hydro­spiro­[indoline-3,3′-pyrrolizin]-2-one

In the title compound, C(22)H(23)N(3)O(4), the tolyl ring is almost perpendicular [83.86 (7)°] to the best plane through the eight atoms of the pyrrolizidine ring system. The mol­ecular conformation is stabilized by an intra­molecular O—H⋯O hydrogen bond. The crystal packing features inversion dimer...

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Detalles Bibliográficos
Autores principales: Sathya, S., Bhaskaran, Sundari, Usha, G., Sivakumar, N., Bakthadoss, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274974/
https://www.ncbi.nlm.nih.gov/pubmed/22346919
http://dx.doi.org/10.1107/S1600536811055449
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author Sathya, S.
Bhaskaran, Sundari
Usha, G.
Sivakumar, N.
Bakthadoss, M.
author_facet Sathya, S.
Bhaskaran, Sundari
Usha, G.
Sivakumar, N.
Bakthadoss, M.
author_sort Sathya, S.
collection PubMed
description In the title compound, C(22)H(23)N(3)O(4), the tolyl ring is almost perpendicular [83.86 (7)°] to the best plane through the eight atoms of the pyrrolizidine ring system. The mol­ecular conformation is stabilized by an intra­molecular O—H⋯O hydrogen bond. The crystal packing features inversion dimers with R (2) (2)(8) motifs linked by pairs of N—H⋯O hydrogen bonds.
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spelling pubmed-32749742012-02-15 2′-Hy­droxy­methyl-1′-(4-methyl­phen­yl)-2′-nitro-1′,2′,5′,6′,7′,7a′-hexa­hydro­spiro­[indoline-3,3′-pyrrolizin]-2-one Sathya, S. Bhaskaran, Sundari Usha, G. Sivakumar, N. Bakthadoss, M. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(22)H(23)N(3)O(4), the tolyl ring is almost perpendicular [83.86 (7)°] to the best plane through the eight atoms of the pyrrolizidine ring system. The mol­ecular conformation is stabilized by an intra­molecular O—H⋯O hydrogen bond. The crystal packing features inversion dimers with R (2) (2)(8) motifs linked by pairs of N—H⋯O hydrogen bonds. International Union of Crystallography 2012-01-07 /pmc/articles/PMC3274974/ /pubmed/22346919 http://dx.doi.org/10.1107/S1600536811055449 Text en © Sathya et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Sathya, S.
Bhaskaran, Sundari
Usha, G.
Sivakumar, N.
Bakthadoss, M.
2′-Hy­droxy­methyl-1′-(4-methyl­phen­yl)-2′-nitro-1′,2′,5′,6′,7′,7a′-hexa­hydro­spiro­[indoline-3,3′-pyrrolizin]-2-one
title 2′-Hy­droxy­methyl-1′-(4-methyl­phen­yl)-2′-nitro-1′,2′,5′,6′,7′,7a′-hexa­hydro­spiro­[indoline-3,3′-pyrrolizin]-2-one
title_full 2′-Hy­droxy­methyl-1′-(4-methyl­phen­yl)-2′-nitro-1′,2′,5′,6′,7′,7a′-hexa­hydro­spiro­[indoline-3,3′-pyrrolizin]-2-one
title_fullStr 2′-Hy­droxy­methyl-1′-(4-methyl­phen­yl)-2′-nitro-1′,2′,5′,6′,7′,7a′-hexa­hydro­spiro­[indoline-3,3′-pyrrolizin]-2-one
title_full_unstemmed 2′-Hy­droxy­methyl-1′-(4-methyl­phen­yl)-2′-nitro-1′,2′,5′,6′,7′,7a′-hexa­hydro­spiro­[indoline-3,3′-pyrrolizin]-2-one
title_short 2′-Hy­droxy­methyl-1′-(4-methyl­phen­yl)-2′-nitro-1′,2′,5′,6′,7′,7a′-hexa­hydro­spiro­[indoline-3,3′-pyrrolizin]-2-one
title_sort 2′-hy­droxy­methyl-1′-(4-methyl­phen­yl)-2′-nitro-1′,2′,5′,6′,7′,7a′-hexa­hydro­spiro­[indoline-3,3′-pyrrolizin]-2-one
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3274974/
https://www.ncbi.nlm.nih.gov/pubmed/22346919
http://dx.doi.org/10.1107/S1600536811055449
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