(3R,4R,4aS,7aR,12bS)-3-Cyclo­propyl­methyl-4a,9-dihy­droxy-3-methyl-7-oxo-2,3,4,4a,5,6,7,7a-octa­hydro-1H-4,12-methano­benzofuro[3,2-e]isoquinolin-3-ium bromide

The title compound, C(21)H(26)NO(4) (+)·Br(−), also known as R-methyl­naltrexone (MNTX) bromide, is a selective peripher­ally acting μ-opioid receptor antagonist with a oroxymorphone skeleton, synthesized by hydroxyl protection, N-methyl­ation, deprotection and anion exchange of naltrexone. It compr...

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Detalles Bibliográficos
Autores principales: Chen, Xiangfeng, Zong, Zaiwei, Du, Youguo, Li, Jianguo, Sun, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275079/
https://www.ncbi.nlm.nih.gov/pubmed/22347024
http://dx.doi.org/10.1107/S1600536812000645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275079/
https://www.ncbi.nlm.nih.gov/pubmed/22347024
http://dx.doi.org/10.1107/S1600536812000645

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