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Ethyl 2-(1,3-benzodioxol-5-yl)-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazole-5-carboxylate
In the title compound, C(24)H(25)N(3)O(5), the benzimidazole and benzodioxole ring systems are each approximately planar [maximum deviations = 0.043 (1) and 0.036 (1) Å, respectively]. Their mean planes form a dihedral angle of 42.85 (4)°. The pyrrolidine ring has an envelope conformation with one o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275223/ https://www.ncbi.nlm.nih.gov/pubmed/22347079 http://dx.doi.org/10.1107/S1600536812001420 |
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author | Yoon, Yeong Keng Ali, Mohamed Ashraf Wei, Ang Chee Asik, Safra Izuani Jama Razak, Ibrahim Abdul |
author_facet | Yoon, Yeong Keng Ali, Mohamed Ashraf Wei, Ang Chee Asik, Safra Izuani Jama Razak, Ibrahim Abdul |
author_sort | Yoon, Yeong Keng |
collection | PubMed |
description | In the title compound, C(24)H(25)N(3)O(5), the benzimidazole and benzodioxole ring systems are each approximately planar [maximum deviations = 0.043 (1) and 0.036 (1) Å, respectively]. Their mean planes form a dihedral angle of 42.85 (4)°. The pyrrolidine ring has an envelope conformation with one of the methylene C atoms forming the flap. In the crystal, weak C—H⋯O hydrogen bonds link the molecules into a three-dimensional network. The crystal packing is further stabillized by weak π–π interactions between the benzene rings within the benzimidazole ring system [centroid–centroid distance = 3.7955 (7) Å]. A weak C—H⋯π interaction involving the benzodioxole ring is also present. |
format | Online Article Text |
id | pubmed-3275223 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-32752232012-02-15 Ethyl 2-(1,3-benzodioxol-5-yl)-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazole-5-carboxylate Yoon, Yeong Keng Ali, Mohamed Ashraf Wei, Ang Chee Asik, Safra Izuani Jama Razak, Ibrahim Abdul Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(24)H(25)N(3)O(5), the benzimidazole and benzodioxole ring systems are each approximately planar [maximum deviations = 0.043 (1) and 0.036 (1) Å, respectively]. Their mean planes form a dihedral angle of 42.85 (4)°. The pyrrolidine ring has an envelope conformation with one of the methylene C atoms forming the flap. In the crystal, weak C—H⋯O hydrogen bonds link the molecules into a three-dimensional network. The crystal packing is further stabillized by weak π–π interactions between the benzene rings within the benzimidazole ring system [centroid–centroid distance = 3.7955 (7) Å]. A weak C—H⋯π interaction involving the benzodioxole ring is also present. International Union of Crystallography 2012-01-21 /pmc/articles/PMC3275223/ /pubmed/22347079 http://dx.doi.org/10.1107/S1600536812001420 Text en © Yoon et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Yoon, Yeong Keng Ali, Mohamed Ashraf Wei, Ang Chee Asik, Safra Izuani Jama Razak, Ibrahim Abdul Ethyl 2-(1,3-benzodioxol-5-yl)-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazole-5-carboxylate |
title | Ethyl 2-(1,3-benzodioxol-5-yl)-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazole-5-carboxylate |
title_full | Ethyl 2-(1,3-benzodioxol-5-yl)-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazole-5-carboxylate |
title_fullStr | Ethyl 2-(1,3-benzodioxol-5-yl)-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazole-5-carboxylate |
title_full_unstemmed | Ethyl 2-(1,3-benzodioxol-5-yl)-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazole-5-carboxylate |
title_short | Ethyl 2-(1,3-benzodioxol-5-yl)-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1H-benzimidazole-5-carboxylate |
title_sort | ethyl 2-(1,3-benzodioxol-5-yl)-1-[3-(2-oxopyrrolidin-1-yl)propyl]-1h-benzimidazole-5-carboxylate |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275223/ https://www.ncbi.nlm.nih.gov/pubmed/22347079 http://dx.doi.org/10.1107/S1600536812001420 |
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