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3β-Acet­oxy-5α-cholestan-6-one 2-cyano­acetyl­hydrazone

The asymmetric unit of the title compound, C(32)H(51)N(3)O(3), consists of two crystallographically independent mol­ecules, A and B; the 2-methyl­pentane group of mol­ecule A and the propane group of mol­ecule B are each disordered over two sets of sites, with refined site-occupancies of 0.825 (5):0...

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Detalles Bibliográficos
Autores principales: Yusufzai, Samina Khan, Osman, Hasnah, Sulaiman, Othman, Arshad, Suhana, Razak, Ibrahim Abdul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275224/
https://www.ncbi.nlm.nih.gov/pubmed/22347080
http://dx.doi.org/10.1107/S1600536812001432
Descripción
Sumario:The asymmetric unit of the title compound, C(32)H(51)N(3)O(3), consists of two crystallographically independent mol­ecules, A and B; the 2-methyl­pentane group of mol­ecule A and the propane group of mol­ecule B are each disordered over two sets of sites, with refined site-occupancies of 0.825 (5):0.175 (5) and 0.630 (18):0.370 (18), respectively. In both mol­ecules, the three cyclo­hexane rings in the steroid fused ring systems adopt chair conformations while the cyclo­pentane rings adopt envelope and twist conformations in mol­ecules A and B, respectively. In the crystal, N—H⋯O and C—H⋯O hydrogen bonds link the two independent mol­ecules together, generating R (2) (1)(7) and R (2) (2)(8) ring motifs.