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2-Amino-N-[3-(2-chlorobenzoyl)-5-ethylthiophen-2-yl]acetamide
In the title compound, C(15)H(15)ClN(2)O(2)S, the 2-aminoacetamide N—C(=O)—C—N unit is approximately planar, with an r.m.s. deviation of 0.020 (4) Å. The central thiophene ring makes dihedral angles of 7.84 (11) and 88.11 (11)°, respectively, with the 2-aminoacetamide unit and the 2-chlorophenyl...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275284/ https://www.ncbi.nlm.nih.gov/pubmed/22347140 http://dx.doi.org/10.1107/S1600536812003261 |
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author | Fun, Hoong-Kun Chantrapromma, Suchada Dayananda, A. S. Yathirajan, H. S. Ramesha, A. R. |
author_facet | Fun, Hoong-Kun Chantrapromma, Suchada Dayananda, A. S. Yathirajan, H. S. Ramesha, A. R. |
author_sort | Fun, Hoong-Kun |
collection | PubMed |
description | In the title compound, C(15)H(15)ClN(2)O(2)S, the 2-aminoacetamide N—C(=O)—C—N unit is approximately planar, with an r.m.s. deviation of 0.020 (4) Å. The central thiophene ring makes dihedral angles of 7.84 (11) and 88.11 (11)°, respectively, with the 2-aminoacetamide unit and the 2-chlorophenyl ring. An intramolecular N—H⋯O hydrogen bond generates an S(6) ring motif. In the crystal, molecules are linked by an N—H⋯O hydrogen bond and weak C—H⋯O interactions into a chain along the c axis. A C—H⋯π interaction is also present. |
format | Online Article Text |
id | pubmed-3275284 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-32752842012-02-15 2-Amino-N-[3-(2-chlorobenzoyl)-5-ethylthiophen-2-yl]acetamide Fun, Hoong-Kun Chantrapromma, Suchada Dayananda, A. S. Yathirajan, H. S. Ramesha, A. R. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(15)H(15)ClN(2)O(2)S, the 2-aminoacetamide N—C(=O)—C—N unit is approximately planar, with an r.m.s. deviation of 0.020 (4) Å. The central thiophene ring makes dihedral angles of 7.84 (11) and 88.11 (11)°, respectively, with the 2-aminoacetamide unit and the 2-chlorophenyl ring. An intramolecular N—H⋯O hydrogen bond generates an S(6) ring motif. In the crystal, molecules are linked by an N—H⋯O hydrogen bond and weak C—H⋯O interactions into a chain along the c axis. A C—H⋯π interaction is also present. International Union of Crystallography 2012-01-31 /pmc/articles/PMC3275284/ /pubmed/22347140 http://dx.doi.org/10.1107/S1600536812003261 Text en © Fun et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Fun, Hoong-Kun Chantrapromma, Suchada Dayananda, A. S. Yathirajan, H. S. Ramesha, A. R. 2-Amino-N-[3-(2-chlorobenzoyl)-5-ethylthiophen-2-yl]acetamide |
title | 2-Amino-N-[3-(2-chlorobenzoyl)-5-ethylthiophen-2-yl]acetamide |
title_full | 2-Amino-N-[3-(2-chlorobenzoyl)-5-ethylthiophen-2-yl]acetamide |
title_fullStr | 2-Amino-N-[3-(2-chlorobenzoyl)-5-ethylthiophen-2-yl]acetamide |
title_full_unstemmed | 2-Amino-N-[3-(2-chlorobenzoyl)-5-ethylthiophen-2-yl]acetamide |
title_short | 2-Amino-N-[3-(2-chlorobenzoyl)-5-ethylthiophen-2-yl]acetamide |
title_sort | 2-amino-n-[3-(2-chlorobenzoyl)-5-ethylthiophen-2-yl]acetamide |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275284/ https://www.ncbi.nlm.nih.gov/pubmed/22347140 http://dx.doi.org/10.1107/S1600536812003261 |
work_keys_str_mv | AT funhoongkun 2aminon32chlorobenzoyl5ethylthiophen2ylacetamide AT chantraprommasuchada 2aminon32chlorobenzoyl5ethylthiophen2ylacetamide AT dayanandaas 2aminon32chlorobenzoyl5ethylthiophen2ylacetamide AT yathirajanhs 2aminon32chlorobenzoyl5ethylthiophen2ylacetamide AT rameshaar 2aminon32chlorobenzoyl5ethylthiophen2ylacetamide |