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Oncostatin M induces heat hypersensitivity by gp130-dependent sensitization of TRPV1 in sensory neurons
Oncostatin M (OSM) is a member of the interleukin-6 cytokine family and regulates eg. gene activation, cell survival, proliferation and differentiation. OSM binds to a receptor complex consisting of the ubiquitously expressed signal transducer gp130 and the ligand binding OSM receptor subunit, which...
Autores principales: | Langeslag, Michiel, Constantin, Cristina E, Andratsch, Manfred, Quarta, Serena, Mair, Norbert, Kress, Michaela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275481/ https://www.ncbi.nlm.nih.gov/pubmed/22196363 http://dx.doi.org/10.1186/1744-8069-7-102 |
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