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Increased sensitivity of next generation sequencing-based expression profiling after globin reduction in human blood RNA
BACKGROUND: Transcriptome analysis is of great interest in clinical research, where significant differences between individuals can be translated into biomarkers of disease. Although next generation sequencing provides robust, comparable and highly informative expression profiling data, with several...
Autores principales: | Mastrokolias, Anastasios, den Dunnen, Johan T, van Ommen, GertJan B, 't Hoen, Peter AC, van Roon-Mom, Willeke MC |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275489/ https://www.ncbi.nlm.nih.gov/pubmed/22257641 http://dx.doi.org/10.1186/1471-2164-13-28 |
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