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Partners in crime: the TGFβ and MAPK pathways in cancer progression

The TGFβ and Ras-MAPK pathways play critical roles in cell development and cell cycle regulation, as well as in tumor formation and metastasis. In the absence of cellular transformation, these pathways operate in opposition to one another, where TGFβ maintains an undifferentiated cell state and supp...

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Detalles Bibliográficos
Autores principales: Chapnick, Douglas A, Warner, Lisa, Bernet, Jennifer, Rao, Timsi, Liu, Xuedong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275500/
https://www.ncbi.nlm.nih.gov/pubmed/22204556
http://dx.doi.org/10.1186/2045-3701-1-42

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