Long-Term Gene Therapy Causes Transgene-Specific Changes in the Morphology of Regenerating Retinal Ganglion Cells

Recombinant adeno-associated viral (rAAV) vectors can be used to introduce neurotrophic genes into injured CNS neurons, promoting survival and axonal regeneration. Gene therapy holds much promise for the treatment of neurotrauma and neurodegenerative diseases; however, neurotrophic factors are known...

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Detalles Bibliográficos
Autores principales: Rodger, Jennifer, Drummond, Eleanor S., Hellström, Mats, Robertson, Donald, Harvey, Alan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275572/
https://www.ncbi.nlm.nih.gov/pubmed/22347429
http://dx.doi.org/10.1371/journal.pone.0031061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275572/
https://www.ncbi.nlm.nih.gov/pubmed/22347429
http://dx.doi.org/10.1371/journal.pone.0031061

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