Cargando…

KLC1-ALK: A Novel Fusion in Lung Cancer Identified Using a Formalin-Fixed Paraffin-Embedded Tissue Only

The promising results of anaplastic lymphoma kinase (ALK) inhibitors have changed the significance of ALK fusions in several types of cancer. These fusions are no longer mere research targets or diagnostic markers, but they are now directly linked to the therapeutic benefit of patients. However, mos...

Descripción completa

Detalles Bibliográficos
Autores principales:	Togashi, Yuki, Soda, Manabu, Sakata, Seiji, Sugawara, Emiko, Hatano, Satoko, Asaka, Reimi, Nakajima, Takashi, Mano, Hiroyuki, Takeuchi, Kengo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275577/ https://www.ncbi.nlm.nih.gov/pubmed/22347464 http://dx.doi.org/10.1371/journal.pone.0031323

Ejemplares similares

Establishment of a novel protocol for formalin-fixed paraffin-embedded organoids and spheroids
por: Yoshimoto, Shohei, et al.
Publicado: (2023)

Activity of EGFR-tyrosine kinase and ALK inhibitors for EML4–ALK-rearranged non–small–cell lung cancer harbored coexisting EGFR mutation
por: Miyanaga, Akihiko, et al.
Publicado: (2013)

Serial liquid biopsies for detection of treatment failure and profiling of resistance mechanisms in KLC1–ALK-rearranged lung cancer
por: Dietz, Steffen, et al.
Publicado: (2019)

MicroSEC filters sequence errors for formalin-fixed and paraffin-embedded samples
por: Ikegami, Masachika, et al.
Publicado: (2021)

Epithelioid cell histiocytoma with SQSTM1-ALK fusion: a case report
por: Nakayama, Ryuko, et al.
Publicado: (2018)

Functional comparison of anti-restriction and anti-methylation activities of ArdA, KlcA, and KlcA(HS) from Klebsiella pneumoniae
por: Chen, Huimin, et al.
Publicado: (2022)

Performance of a novel KRAS mutation assay for formalin-fixed paraffin embedded tissues of colorectal cancer
por: Sakai, Kazuko, et al.
Publicado: (2015)

Clinical and prognostic significance of aberrant T-cell marker expression in 225 cases of de novo diffuse large B-cell lymphoma and 276 cases of other B-cell lymphomas
por: Tsuyama, Naoko, et al.
Publicado: (2017)

Massively parallel sequencing of formalin-fixed paraffin-embedded tissues
por: Erlich, Rachel L, et al.
Publicado: (2012)

Virus characterization and discovery in formalin-fixed paraffin-embedded tissues
por: Bodewes, Rogier, et al.
Publicado: (2015)

Profiling chromatin accessibility in formalin-fixed paraffin-embedded samples
por: Zhang, Hua, et al.
Publicado: (2022)

Altered expression of KLC3 may affect semen parameters
por: Kargar- Dastjerdy, Pegah, et al.
Publicado: (2016)

Expression profiling with RNA from formalin-fixed, paraffin-embedded material
por: Oberli, Andrea, et al.
Publicado: (2008)

Multiple immunofluorescence labelling of formalin-fixed paraffin-embedded (FFPE) tissue
por: Robertson, David, et al.
Publicado: (2008)

Gene expression profiles of gliomas in formalin-fixed paraffin-embedded material
por: Gravendeel, L A M, et al.
Publicado: (2012)

Toward deciphering proteomes of formalin-fixed paraffin-embedded (FFPE) tissues
por: Magdeldin, Sameh, et al.
Publicado: (2012)

Proteomic Sample Preparation from Formalin Fixed and Paraffin Embedded Tissue
por: Wiśniewski, Jacek R.
Publicado: (2013)

Molecular Markers for Prostate Cancer in Formalin-Fixed Paraffin-Embedded Tissues
por: Sequeiros, Tamara, et al.
Publicado: (2013)

Deep Clonal Profiling of Formalin Fixed Paraffin Embedded Clinical Samples
por: Holley, Tara, et al.
Publicado: (2012)

Epigenomic analysis of formalin-fixed paraffin-embedded samples by CUT&Tag
por: Henikoff, Steven, et al.
Publicado: (2023)

Comprehensive assay for the molecular profiling of cancer by target enrichment from formalin‐fixed paraffin‐embedded specimens
por: Kohsaka, Shinji, et al.
Publicado: (2019)

TERT Promoter Mutation and Extent of Thyroidectomy in Patients with 1–4 cm Intrathyroidal Papillary Carcinoma
por: Ebina, Aya, et al.
Publicado: (2020)

Variants in PRKCE and KLC1, Potential Regulators of Type I Psoriasis
por: Xing, Jianxiao, et al.
Publicado: (2022)

Evaluation of formalin-fixed paraffin-embedded tissues in the proteomic analysis of parathyroid glands
por: Donadio, Elena, et al.
Publicado: (2011)

PrP(Sc )detection in formalin-fixed paraffin-embedded tissue by ELISA
por: Nicholson, Eric M, et al.
Publicado: (2011)

PCR for the Diagnosis of Abdominal Angiostrongyliasis in Formalin-Fixed Paraffin-Embedded Human Tissue
por: Rodriguez, Rubens, et al.
Publicado: (2014)

Robustness of Next Generation Sequencing on Older Formalin-Fixed Paraffin-Embedded Tissue
por: Carrick, Danielle Mercatante, et al.
Publicado: (2015)

Optimization of gene expression microarray protocol for formalin-fixed paraffin-embedded tissues
por: Belder, Nevin, et al.
Publicado: (2016)

The Utilization of Formalin Fixed-Paraffin-Embedded Specimens in High Throughput Genomic Studies
por: Zhang, Pan, et al.
Publicado: (2017)

RNA-seq transcriptome analysis of formalin fixed, paraffin-embedded canine meningioma
por: Grenier, Jennifer K., et al.
Publicado: (2017)

Formalin-Fixed and Paraffin-Embedded Samples for Next Generation Sequencing: Problems and Solutions
por: Cazzato, Gerardo, et al.
Publicado: (2021)

Biomarker Analysis of Formalin-Fixed Paraffin-Embedded Clinical Tissues Using Proteomics
por: Obi, Ekenedirichukwu N., et al.
Publicado: (2023)

Automated array-CGH optimized for archival formalin-fixed, paraffin-embedded tumor material
por: Joosse, Simon A, et al.
Publicado: (2007)

Transcriptome profiling from formalin-fixed, paraffin-embedded tumor specimens by RNA-seq
por: Qu, Kunbin, et al.
Publicado: (2010)

microRNA and protein expression in breast cancer formalin-fixed paraffin-embedded samples
por: Gámez-Pozo, A, et al.
Publicado: (2011)

Whole-Genome Gene Expression Profiling of Formalin-Fixed, Paraffin-Embedded Tissue Samples
por: April, Craig, et al.
Publicado: (2009)

Comparison of Methods for the Extraction of DNA from Formalin-Fixed, Paraffin-Embedded Archival Tissues
por: Sengüven, Burcu, et al.
Publicado: (2014)

Applications of mass spectrometry for quantitative protein analysis in formalin-fixed paraffin-embedded tissues
por: Steiner, Carine, et al.
Publicado: (2014)

Unmasking of complements using proteinase-K in formalin fixed paraffin embedded renal biopsies
por: Nada, R., et al.
Publicado: (2016)

Preparation of Formalin-fixed Paraffin-embedded Tissue Cores for both RNA and DNA Extraction
por: Patel, Palak G., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_666dgfdukhich5alikrcbl56qa