CTCF Mediates the Cell-Type Specific Spatial Organization of the Kcnq5 Locus and the Local Gene Regulation

Chromatin loops play important roles in the dynamic spatial organization of genes in the nucleus. Growing evidence has revealed that the multivalent functional zinc finger protein CCCTC-binding factor (CTCF) is a master regulator of genome spatial organization, and mediates the ubiquitous chromatin...

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Detalles Bibliográficos
Autores principales: Ren, Licheng, Wang, Yang, Shi, Minglei, Wang, Xiaoning, Yang, Zhong, Zhao, Zhihu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275579/
https://www.ncbi.nlm.nih.gov/pubmed/22347474
http://dx.doi.org/10.1371/journal.pone.0031416

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