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Enhancement of metastatic ability by ectopic expression of ST6GalNAcI on a gastric cancer cell line in a mouse model

ST6GalNAcI is a sialyltransferase responsible for the synthesis of sialyl Tn (sTn) antigen which is expressed in a variety of adenocarcinomas including gastric cancer especially in advanced cases, but the roles of ST6GalNAcI and sTn in cancer progression are largely unknown. We generated sTn-express...

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Detalles Bibliográficos
Autores principales: Ozaki, Hidenori, Matsuzaki, Hideki, Ando, Hidenobu, Kaji, Hiroyuki, Nakanishi, Hayao, Ikehara, Yuzuru, Narimatsu, Hisashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275730/
https://www.ncbi.nlm.nih.gov/pubmed/22228572
http://dx.doi.org/10.1007/s10585-011-9445-1