Cargando…

GSK3 as a Sensor Determining Cell Fate in the Brain

Glycogen synthase kinase 3 (GSK3) is an unusual serine/threonine kinase that controls many neuronal functions, including neurite outgrowth, synapse formation, neurotransmission, and neurogenesis. It mediates these functions by phosphorylating a wide range of substrates involved in gene transcription...

Descripción completa

Detalles Bibliográficos
Autor principal:	Cole, Adam R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275790/ https://www.ncbi.nlm.nih.gov/pubmed/22363258 http://dx.doi.org/10.3389/fnmol.2012.00004

Ejemplares similares

GSK3α and GSK3β Phosphorylate Arc and Regulate its Degradation
por: Gozdz, Agata, et al.
Publicado: (2017)

Gene regulatory network analysis reveals differences in site-specific cell fate determination in mammalian brain
por: Ertaylan, Gökhan, et al.
Publicado: (2014)

GSK-3β and memory formation
por: Takashima, Akihiko
Publicado: (2012)

The proactive brain and the fate of dead hypotheses
por: Tal, Amir, et al.
Publicado: (2014)

AKT/GSK3 signaling pathway and schizophrenia
por: Emamian, Effat S.
Publicado: (2012)

GSK3 and Alzheimer’s Disease: Facts and Fiction…
por: Kremer, Anna, et al.
Publicado: (2011)

Role of GSK3 Signaling in Neuronal Morphogenesis
por: Kim, Yun Tai, et al.
Publicado: (2011)

A pivotal role of GSK-3 in synaptic plasticity
por: Bradley, Clarrisa A., et al.
Publicado: (2012)

EZH2 Is Essential for Fate Determination in the Mammalian Isthmic Area
por: Wever, Iris, et al.
Publicado: (2019)

GSK-3: Functional Insights from Cell Biology and Animal Models
por: Kaidanovich-Beilin, Oksana, et al.
Publicado: (2011)

Novel Non-phosphorylated Serine 9/21 GSK3β/α Antibodies: Expanding the Tools for Studying GSK3 Regulation
por: Grabinski, Tessa, et al.
Publicado: (2016)

The aged brain: genesis and fate of residual progenitor cells in the subventricular zone
por: Capilla-Gonzalez, Vivian, et al.
Publicado: (2015)

Neurological Functions of the Masterswitch Protein Kinase – Gsk-3
por: Kaidanovich-Beilin, Oksana, et al.
Publicado: (2012)

GSK-3 and Wnt Signaling in Neurogenesis and Bipolar Disorder
por: Valvezan, Alexander J., et al.
Publicado: (2012)

Functions of GSK-3 Signaling in Development of the Nervous System
por: Kim, Woo-Yang, et al.
Publicado: (2011)

GSK-3 Inhibitors: Preclinical and Clinical Focus on CNS
por: Eldar-Finkelman, Hagit, et al.
Publicado: (2011)

Modulation of GSK-3 as a Therapeutic Strategy on Tau Pathologies
por: Medina, Miguel, et al.
Publicado: (2011)

GSK-3β, a pivotal kinase in Alzheimer disease
por: Llorens-Marítin, María, et al.
Publicado: (2014)

The neural stem cell fate determinant TRIM32 regulates complex behavioral traits
por: Hillje, Anna-Lena, et al.
Publicado: (2015)

Beyond cAMP: The Regulation of Akt and GSK3 by Dopamine Receptors
por: Beaulieu, Jean-Martin, et al.
Publicado: (2011)

GSK-3 Mouse Models to Study Neuronal Apoptosis and Neurodegeneration
por: Gómez-Sintes, Raquel, et al.
Publicado: (2011)

Cell Type-Specific Transcriptional Control of Gsk3β in the Developing Mammalian Neocortex
por: Nomura, Tadashi, et al.
Publicado: (2022)

Molecular Machines Determining the Fate of Endocytosed Synaptic Vesicles in Nerve Terminals
por: Fassio, Anna, et al.
Publicado: (2016)

Tcf12 Is Involved in Early Cell-Fate Determination and Subset Specification of Midbrain Dopamine Neurons
por: Mesman, Simone, et al.
Publicado: (2017)

Molecular Mechanisms Governing the Stem Cell’s Fate in Brain Cancer: Factors of Stemness and Quiescence
por: Gulaia, Valeriia, et al.
Publicado: (2018)

Inhibition of GSK3 by lithium, from single molecules to signaling networks
por: Freland, Laure, et al.
Publicado: (2012)

Overexpression of GSK-3β in Adult Tet-OFF GSK-3β Transgenic Mice, and Not During Embryonic or Postnatal Development, Induces Tau Phosphorylation, Neurodegeneration and Learning Deficits
por: Rodríguez-Matellán, Alberto, et al.
Publicado: (2020)

Crosstalk between Cdk5 and GSK3β: Implications for Alzheimer's Disease
por: Engmann, Olivia, et al.
Publicado: (2009)

Acute Ethanol Inhibition of γ Oscillations Is Mediated by Akt and GSK3β
por: Wang, JianGang, et al.
Publicado: (2016)

The Fate of Incoming Stimuli during NREM Sleep is Determined by Spindles and the Phase of the Slow Oscillation
por: Schabus, Manuel, et al.
Publicado: (2012)

Disparate Effects of Lithium and a GSK-3 Inhibitor on Neuronal Oscillatory Activity in Prefrontal Cortex and Hippocampus
por: Nguyen, Tuan, et al.
Publicado: (2018)

Primary Blast-Induced Changes in Akt and GSK(3β) Phosphorylation in Rat Hippocampus
por: Wang, Yushan, et al.
Publicado: (2017)

GSK3β and Tau Protein in Alzheimer’s Disease and Epilepsy
por: Toral-Rios, Danira, et al.
Publicado: (2020)

Differential regulation of collapsin response mediator protein 2 (CRMP2) phosphorylation by GSK3ß and CDK5 following traumatic brain injury
por: Wilson, Sarah M., et al.
Publicado: (2014)

Apolipoprotein E-Mimetic Peptide COG1410 Promotes Autophagy by Phosphorylating GSK-3β in Early Brain Injury Following Experimental Subarachnoid Hemorrhage
por: Li, Xinshen, et al.
Publicado: (2018)

Lithium Inhibits GSK3β and Augments GluN2A Receptor Expression in the Prefrontal Cortex
por: Monaco, Sarah A., et al.
Publicado: (2018)

The GSK-3 Inhibitor CT99021 Enhances the Acquisition of Spatial Learning and the Accuracy of Spatial Memory
por: Lee, Yeseul, et al.
Publicado: (2022)

Probiotic supplement as a promising strategy in early tau pathology prevention: Focusing on GSK-3β?
por: Flynn, Cassandra M., et al.
Publicado: (2023)

microRNAs: key triggers of neuronal cell fate
por: Meza-Sosa, Karla F., et al.
Publicado: (2014)

MicroRNAs and cell fate in cortical and retinal development
por: Cremisi, Federico
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_vh7b84o6lt0948qrk3v5hmfb0e