Decreased Phosphorylation and Increased Methionine Oxidation of α-Synuclein in the Methionine Sulfoxide Reductase A Knockout Mouse

Previously, we have showed that overexpression of methionine-oxidized α-synuclein in methionine sulfoxide reductase A (MsrA) null mutant yeast cells inhibits α-synuclein phosphorylation and increases protein fibrillation. The current studies show that ablation of mouse MsrA gene caused enhanced meth...

Descripción completa

Detalles Bibliográficos
Autores principales: Oien, Derek B., Carrasco, Gonzalo A., Moskovitz, Jackob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3275937/
https://www.ncbi.nlm.nih.gov/pubmed/22332004
http://dx.doi.org/10.4061/2011/721094

Ejemplares similares

Ejemplares similares