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Genome-Wide Analysis to Identify Pathways Affecting Telomere-Initiated Senescence in Budding Yeast
In telomerase-deficient yeast cells, like equivalent mammalian cells, telomeres shorten over many generations until a period of senescence/crisis is reached. After this, a small fraction of cells can escape senescence, principally using recombination-dependent mechanisms. To investigate the pathways...
Autores principales: | Chang, Hsin-Yu, Lawless, Conor, Addinall, Stephen G., Oexle, Sarah, Taschuk, Morgan, Wipat, Anil, Wilkinson, Darren J., Lydall, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276134/ https://www.ncbi.nlm.nih.gov/pubmed/22384331 http://dx.doi.org/10.1534/g3.111.000216 |
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