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Genome-Wide Analysis to Identify Pathways Affecting Telomere-Initiated Senescence in Budding Yeast

In telomerase-deficient yeast cells, like equivalent mammalian cells, telomeres shorten over many generations until a period of senescence/crisis is reached. After this, a small fraction of cells can escape senescence, principally using recombination-dependent mechanisms. To investigate the pathways...

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Detalles Bibliográficos
Autores principales: Chang, Hsin-Yu, Lawless, Conor, Addinall, Stephen G., Oexle, Sarah, Taschuk, Morgan, Wipat, Anil, Wilkinson, Darren J., Lydall, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276134/
https://www.ncbi.nlm.nih.gov/pubmed/22384331
http://dx.doi.org/10.1534/g3.111.000216

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