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Mixed Model Association Mapping for Fusarium Head Blight Resistance in Tunisian-Derived Durum Wheat Populations

Sources of resistance to Fusarium head blight (FHB) in wheat are mostly restricted to Chinese hexaploid genotypes. The effort to incorporate the resistance from hexaploid wheat or wild relatives to cultivated durum wheat (Triticum turgidum L. var. durum Desf.) have not been successful in providing r...

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Autores principales: Ghavami, Farhad, Elias, Elias M., Mamidi, Sujan, Ansari, Omid, Sargolzaei, Mehdi, Adhikari, Tika, Mergoum, Mohamed, Kianian, Shahryar F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276138/
https://www.ncbi.nlm.nih.gov/pubmed/22384332
http://dx.doi.org/10.1534/g3.111.000489
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author Ghavami, Farhad
Elias, Elias M.
Mamidi, Sujan
Ansari, Omid
Sargolzaei, Mehdi
Adhikari, Tika
Mergoum, Mohamed
Kianian, Shahryar F.
author_facet Ghavami, Farhad
Elias, Elias M.
Mamidi, Sujan
Ansari, Omid
Sargolzaei, Mehdi
Adhikari, Tika
Mergoum, Mohamed
Kianian, Shahryar F.
author_sort Ghavami, Farhad
collection PubMed
description Sources of resistance to Fusarium head blight (FHB) in wheat are mostly restricted to Chinese hexaploid genotypes. The effort to incorporate the resistance from hexaploid wheat or wild relatives to cultivated durum wheat (Triticum turgidum L. var. durum Desf.) have not been successful in providing resistance to the level of the donor parents. In this study, we used 171 BC(1)F(6) and 169 BC(1)F(7) lines derived from crossing of four Tunisian tetraploid sources of resistance (Tun7, Tun18, Tun34, Tun36) with durum cultivars ‘Ben,’ ‘Maier,’ ‘Lebsock,’ and ‘Mountrail’ for association studies. The Tun18 and Tun7 FHB resistances were found to be comparable to the best hexaploid wheat sources. A new significant QTL for FHB resistance was identified on the long arm of chromosome 5B (Qfhs.ndsu-5BL) with both association and classical QTL mapping analysis. Linkage disequilibrium (LD) blocks extending up to 40 cM were evident in these populations. The linear mixed model considering the structure (Q or P) and the kinship matrix (K(T)) estimated by restricted maximum likelihood (REML) was identified as the best for association studies in a mixture of wheat populations from a breeding program. The results of association mapping analysis also demonstrated a region on the short arm of chromosome 3B as potentially linked to FHB resistance. This region is in proximity of major FHB resistance gene fhb1 reported in hexaploid wheat. A possibility of having susceptibility or suppressor of resistance gene(s) on durum wheat chromosome 2A was further confirmed in this material, explaining the problem in developing resistant genotypes without counter selection against this region.
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spelling pubmed-32761382012-03-01 Mixed Model Association Mapping for Fusarium Head Blight Resistance in Tunisian-Derived Durum Wheat Populations Ghavami, Farhad Elias, Elias M. Mamidi, Sujan Ansari, Omid Sargolzaei, Mehdi Adhikari, Tika Mergoum, Mohamed Kianian, Shahryar F. G3 (Bethesda) Investigation Sources of resistance to Fusarium head blight (FHB) in wheat are mostly restricted to Chinese hexaploid genotypes. The effort to incorporate the resistance from hexaploid wheat or wild relatives to cultivated durum wheat (Triticum turgidum L. var. durum Desf.) have not been successful in providing resistance to the level of the donor parents. In this study, we used 171 BC(1)F(6) and 169 BC(1)F(7) lines derived from crossing of four Tunisian tetraploid sources of resistance (Tun7, Tun18, Tun34, Tun36) with durum cultivars ‘Ben,’ ‘Maier,’ ‘Lebsock,’ and ‘Mountrail’ for association studies. The Tun18 and Tun7 FHB resistances were found to be comparable to the best hexaploid wheat sources. A new significant QTL for FHB resistance was identified on the long arm of chromosome 5B (Qfhs.ndsu-5BL) with both association and classical QTL mapping analysis. Linkage disequilibrium (LD) blocks extending up to 40 cM were evident in these populations. The linear mixed model considering the structure (Q or P) and the kinship matrix (K(T)) estimated by restricted maximum likelihood (REML) was identified as the best for association studies in a mixture of wheat populations from a breeding program. The results of association mapping analysis also demonstrated a region on the short arm of chromosome 3B as potentially linked to FHB resistance. This region is in proximity of major FHB resistance gene fhb1 reported in hexaploid wheat. A possibility of having susceptibility or suppressor of resistance gene(s) on durum wheat chromosome 2A was further confirmed in this material, explaining the problem in developing resistant genotypes without counter selection against this region. Genetics Society of America 2011-08-01 /pmc/articles/PMC3276138/ /pubmed/22384332 http://dx.doi.org/10.1534/g3.111.000489 Text en Copyright © 2011 Ghavami et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution Unported License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Investigation
Ghavami, Farhad
Elias, Elias M.
Mamidi, Sujan
Ansari, Omid
Sargolzaei, Mehdi
Adhikari, Tika
Mergoum, Mohamed
Kianian, Shahryar F.
Mixed Model Association Mapping for Fusarium Head Blight Resistance in Tunisian-Derived Durum Wheat Populations
title Mixed Model Association Mapping for Fusarium Head Blight Resistance in Tunisian-Derived Durum Wheat Populations
title_full Mixed Model Association Mapping for Fusarium Head Blight Resistance in Tunisian-Derived Durum Wheat Populations
title_fullStr Mixed Model Association Mapping for Fusarium Head Blight Resistance in Tunisian-Derived Durum Wheat Populations
title_full_unstemmed Mixed Model Association Mapping for Fusarium Head Blight Resistance in Tunisian-Derived Durum Wheat Populations
title_short Mixed Model Association Mapping for Fusarium Head Blight Resistance in Tunisian-Derived Durum Wheat Populations
title_sort mixed model association mapping for fusarium head blight resistance in tunisian-derived durum wheat populations
topic Investigation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276138/
https://www.ncbi.nlm.nih.gov/pubmed/22384332
http://dx.doi.org/10.1534/g3.111.000489
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