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A Synthetic Human Kinase Can Control Cell Cycle Progression in Budding Yeast

The DDK kinase complex, composed of Cdc7 and Dbf4, is required for S-phase progression. The two component proteins show different degrees of sequence conservation between human and yeast. Here, we determine that Saccharomyces cerevisiae bearing human CDC7 and DBF4 grows comparably to cells with yeas...

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Detalles Bibliográficos
Autores principales:	Davey, Megan J., Andrighetti, Heather J., Ma, Xiaoli, Brandl, Christopher J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2011
Materias:	Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276143/ https://www.ncbi.nlm.nih.gov/pubmed/22384342 http://dx.doi.org/10.1534/g3.111.000430

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