Replication Stress-Induced Chromosome Breakage Is Correlated with Replication Fork Progression and Is Preceded by Single-Stranded DNA Formation

Chromosome breakage as a result of replication stress has been hypothesized to be the direct consequence of defective replication fork progression, or “collapsed” replication forks. However, direct and genome-wide evidence that collapsed replication forks give rise to chromosome breakage is still la...

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Detalles Bibliográficos
Autores principales: Feng, Wenyi, Di Rienzi, Sara C., Raghuraman, M. K., Brewer, Bonita J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2011
Materias:
Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276152/
https://www.ncbi.nlm.nih.gov/pubmed/22384343
http://dx.doi.org/10.1534/g3.111.000554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276152/
https://www.ncbi.nlm.nih.gov/pubmed/22384343
http://dx.doi.org/10.1534/g3.111.000554

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