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The C57BL/6J Mouse Strain Background Modifies the Effect of a Mutation in Bcl2l2

Bcl2l2 encodes BCL-W, an antiapoptotic member of the BCL-2 family of proteins. Intercross of Bcl2l2 +/− mice on a mixed C57BL/6J, 129S5 background produces Bcl2l2 −/− animals with the expected frequency. In contrast, intercross of Bcl2l2 +/− mice on a congenic C57BL/6J background produces relatively...

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Detalles Bibliográficos
Autores principales:	Navarro, Stefanie J., Trinh, Tuyen, Lucas, Charlotte A., Ross, Andrea J., Waymire, Katrina G., MacGregor, Grant R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2012
Materias:	Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276190/ https://www.ncbi.nlm.nih.gov/pubmed/22384386 http://dx.doi.org/10.1534/g3.111.000778

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