Transient Overexpression of Sonic Hedgehog Alters the Architecture and Mechanical Properties of Trabecular Bone

Bone formation and remodeling involve coordinated interactions between osteoblasts and osteoclasts through signaling networks involving a variety of molecular pathways. We hypothesized that overexpression of Sonic hedgehog (Shh), a morphogen with a crucial role in skeletal development, would stimula...

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Detalles Bibliográficos
Autores principales: Kiuru, Maija, Solomon, Jason, Ghali, Bassem, van der Meulen, Marjolein, Crystal, Ronald G, Hidaka, Chisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons and The American Society for Bone and Mineral Research (ASBMR) 2009
Materias:
Research-Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276343/
https://www.ncbi.nlm.nih.gov/pubmed/19338448
http://dx.doi.org/10.1359/jbmr.090313

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