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A Genomewide Screen for Suppressors of Alu-Mediated Rearrangements Reveals a Role for PIF1
Alu-mediated rearrangement of tumor suppressor genes occurs frequently during carcinogenesis. In breast cancer, this mechanism contributes to loss of the wild-type BRCA1 allele in inherited disease and to loss of heterozygosity in sporadic cancer. To identify genes required for suppression of Alu-me...
Autores principales: | Chisholm, Karen M., Aubert, Sarah D., Freese, Krister P., Zakian, Virginia A., King, Mary-Claire, Welcsh, Piri L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276492/ https://www.ncbi.nlm.nih.gov/pubmed/22347400 http://dx.doi.org/10.1371/journal.pone.0030748 |
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