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TLR Signaling Paralyzes Monocyte Chemotaxis through Synergized Effects of p38 MAPK and Global Rap-1 Activation

Toll-like receptors (TLRs) that recognize pathogen associated molecular patterns and chemoattractant receptors (CKRs) that orchestrate leukocyte migration to infected tissue are two arms of host innate immunity. Although TLR signaling induces synthesis and secretion of proinflammatory cytokines and...

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Detalles Bibliográficos
Autores principales:	Yi, Ling, Chandrasekaran, Prabha, Venkatesan, Sundararajan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276499/ https://www.ncbi.nlm.nih.gov/pubmed/22347375 http://dx.doi.org/10.1371/journal.pone.0030404

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