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Systematic Detection of Epistatic Interactions Based on Allele Pair Frequencies

Epistatic genetic interactions are key for understanding the genetic contribution to complex traits. Epistasis is always defined with respect to some trait such as growth rate or fitness. Whereas most existing epistasis screens explicitly test for a trait, it is also possible to implicitly test for...

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Detalles Bibliográficos
Autores principales: Ackermann, Marit, Beyer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276547/
https://www.ncbi.nlm.nih.gov/pubmed/22346757
http://dx.doi.org/10.1371/journal.pgen.1002463