Cargando…
Subcellular Location of PKA Controls Striatal Plasticity: Stochastic Simulations in Spiny Dendrites
Dopamine release in the striatum has been implicated in various forms of reward dependent learning. Dopamine leads to production of cAMP and activation of protein kinase A (PKA), which are involved in striatal synaptic plasticity and learning. PKA and its protein targets are not diffusely located th...
Autores principales: | Oliveira, Rodrigo F., Kim, MyungSook, Blackwell, Kim T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276550/ https://www.ncbi.nlm.nih.gov/pubmed/22346744 http://dx.doi.org/10.1371/journal.pcbi.1002383 |
Ejemplares similares
-
Transient Calcium and Dopamine Increase PKA Activity and DARPP-32 Phosphorylation
por: Lindskog, Maria, et al.
Publicado: (2006) -
The Role of Type 4 Phosphodiesterases in Generating Microdomains of cAMP: Large Scale Stochastic Simulations
por: Oliveira, Rodrigo F., et al.
Publicado: (2010) -
The Effects of NMDA Subunit Composition on Calcium Influx and Spike Timing-Dependent Plasticity in Striatal Medium Spiny Neurons
por: Evans, Rebekah C., et al.
Publicado: (2012) -
Synaptically driven state transitions in distal dendrites of striatal spiny neurons
por: Plotkin, Joshua L., et al.
Publicado: (2011) -
Neuregulin-4 Is Required for the Growth and Elaboration of Striatal Medium Spiny Neuron Dendrites
por: Paramo, Blanca, et al.
Publicado: (2019)