Cargando…
Sequence Polymorphism, Segmental Recombination and Toggling Amino Acid Residues within the DBL3X Domain of the VAR2CSA Placental Malaria Antigen
Plasmodium falciparum malaria remains one of the world's foremost health problems, primarily in highly endemic regions such as Sub-Saharan Africa, where it is responsible for substantial morbidity, mortality and economic losses. Malaria is a significant cause of severe disease and death in preg...
Autores principales: | Talundzic, Eldin, Shah, Sheel, Fawole, Ope, Owino, Simon, Moore, Julie M., Peterson, David S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276574/ https://www.ncbi.nlm.nih.gov/pubmed/22347496 http://dx.doi.org/10.1371/journal.pone.0031565 |
Ejemplares similares
-
Polymorphic Molecular Signatures in Variable Regions of the Plasmodium falciparum var2csa DBL3x Domain Are Associated with Virulence in Placental Malaria
por: Talundzic, Eldin, et al.
Publicado: (2022) -
Induction of strain-transcendent antibodies to placental-type isolates with VAR2CSA DBL3 or DBL5 recombinant proteins
por: Avril, Marion, et al.
Publicado: (2011) -
Structure of the DBL3X-DBL4ε region of the VAR2CSA placental malaria vaccine candidate: insight into DBL domain interactions
por: Gangnard, Stéphane, et al.
Publicado: (2015) -
Epitope Mapping and Topographic Analysis of VAR2CSA DBL3X Involved in P. falciparum Placental Sequestration
por: Dahlbäck, Madeleine, et al.
Publicado: (2006) -
Insight into Antigenic Diversity of VAR2CSA-DBL5ε Domain from Multiple Plasmodium falciparum Placental Isolates
por: Gnidehou, Sédami, et al.
Publicado: (2010)