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Ablation of LMO4 in glutamatergic neurons impairs leptin control of fat metabolism

The LIM domain only 4 (LMO4) protein is expressed in the hypothalamus, but its function there is not known. Using mice with LMO4 ablated in postnatal glutamatergic neurons, including most neurons of the paraventricular (PVN) and ventromedial (VMH) hypothalamic nuclei where LMO4 is expressed, we aske...

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Detalles Bibliográficos
Autores principales: Zhou, Xun, Gomez-Smith, Mariana, Qin, Zhaohong, Duquette, Philippe M., Cardenas-Blanco, Arturo, Rai, Punarpreet S., Harper, Mary-Ellen, Tsai, Eve C., Anisman, Hymie, Chen, Hsiao-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SP Birkhäuser Verlag Basel 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276759/
https://www.ncbi.nlm.nih.gov/pubmed/21874351
http://dx.doi.org/10.1007/s00018-011-0794-3