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Morphine metabolism, transport and brain disposition
The chemical structures of morphine and its metabolites are closely related to the clinical effects of drugs (analgesia and side-effects) and to their capability to cross the Blood Brain Barrier (BBB). Morphine-6-glucuronide (M6G) and Morphine-3-glucuronide (M3G) are both highly hydrophilic, but onl...
Autores principales: | De Gregori, Simona, De Gregori, Manuela, Ranzani, Guglielmina Nadia, Allegri, Massimo, Minella, Cristina, Regazzi, Mario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276770/ https://www.ncbi.nlm.nih.gov/pubmed/22193538 http://dx.doi.org/10.1007/s11011-011-9274-6 |
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