Hypofractionated Radiotherapy as Local Hemostatic Agent in Advanced Cancer

PURPOSE: Tumor bleeding continues to remain a challenge in an oncological setting, and radiotherapy has been studied as a local hemostatic agent. We studied the role of local radiotherapy in controlling bleeding at our center. MATERIALS AND METHODS: We reviewed 25 treated cases (cancer urinary bladd...

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Detalles Bibliográficos
Autores principales: Rasool, Malik Tariq, Manzoor, Najmi Arshad, Mustafa, Syed Arshad, Maqbool, Lone Mohammad, Afroz, Fir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276819/
https://www.ncbi.nlm.nih.gov/pubmed/22346046
http://dx.doi.org/10.4103/0973-1075.92339
Descripción
Sumario:PURPOSE: Tumor bleeding continues to remain a challenge in an oncological setting, and radiotherapy has been studied as a local hemostatic agent. We studied the role of local radiotherapy in controlling bleeding at our center. MATERIALS AND METHODS: We reviewed 25 treated cases (cancer urinary bladder: 12, lung cancer: 5, cervical cancer: 4, uterine cancer: 1, rectal cancer: 2, schwanoma: 1) at our center from March 2008 to December 2010. All patients had either an advanced or recurrent disease. Radiotherapy schedule was either 20 Gray in 5 fractions or 15 Gray in 5 fractions and was delivered with Cobalt 60. RESULTS AND CONCLUSION: Of 25 patients, 22 (88%) responded, and there was complete cessation of bleeding. Both 15 Gray and 20 Gray dose schedule had equal efficacy. Treatment was well tolerated without any intermission. Radiotherapy is a safe and effective option in controlling tumor bleeding.

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