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A STUDY ON THE MANAGEMENT OF HIDRADENITIS SUPPURATIVA WITH RETINOIDS AND SURGICAL EXCISION

BACKGROUND: Hidradenitis suppurativa is a chronic skin condition involving the apocrine glandular zones. Affected patients may present with acute abscesses, but the condition often progresses to a chronic state with persistent pain, sepsis, sinus tract, fistula formation, purulent discharge, and der...

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Autores principales: Puri, Neerja, Talwar, Ashutosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276889/
https://www.ncbi.nlm.nih.gov/pubmed/22345763
http://dx.doi.org/10.4103/0019-5154.91821
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author Puri, Neerja
Talwar, Ashutosh
author_facet Puri, Neerja
Talwar, Ashutosh
author_sort Puri, Neerja
collection PubMed
description BACKGROUND: Hidradenitis suppurativa is a chronic skin condition involving the apocrine glandular zones. Affected patients may present with acute abscesses, but the condition often progresses to a chronic state with persistent pain, sepsis, sinus tract, fistula formation, purulent discharge, and dermal scarring. The treatment of patients with severe disease can be difficult and may require complex surgical intervention. MATERIALS AND METHODS: For this study, we selected 30 patients from the outpatient department. The patients were divided into two groups of 15 patients each. In patients of group I, oral acitretin 0.5 mg/kg body weight was given alone. Oral acitretin was given for a period of 12 weeks, and follow-up of the patients was done every 4 weeks for a period of 6 months. In patients of group II, oral acitretin 0.5 mg/kg was given plus a wide surgical excision was done. RESULTS AND DISCUSSION: In our study, the commonest site of involvement of hidradenitis suppurativa was axilla in 83.3% patients, perineum was involved in 13.3% patients, and periumbilical involvement was seen in 3.3% patients. The commonest clinical feature was nodules seen in 90% patients; pain was seen in 60% patients, dermal scarring in 73.3% patients, malodorous discharge in 33.3% patients, abscess in 30% patients, and fistulous tracts were seen in 20% patients. The recurrence rate was low (20%) in group II patients in whom oral acitretin was given plus surgical excision was done as compared with group I (40%) in whom oral acitretin was given alone.
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spelling pubmed-32768892012-02-16 A STUDY ON THE MANAGEMENT OF HIDRADENITIS SUPPURATIVA WITH RETINOIDS AND SURGICAL EXCISION Puri, Neerja Talwar, Ashutosh Indian J Dermatol Therapeutic Round BACKGROUND: Hidradenitis suppurativa is a chronic skin condition involving the apocrine glandular zones. Affected patients may present with acute abscesses, but the condition often progresses to a chronic state with persistent pain, sepsis, sinus tract, fistula formation, purulent discharge, and dermal scarring. The treatment of patients with severe disease can be difficult and may require complex surgical intervention. MATERIALS AND METHODS: For this study, we selected 30 patients from the outpatient department. The patients were divided into two groups of 15 patients each. In patients of group I, oral acitretin 0.5 mg/kg body weight was given alone. Oral acitretin was given for a period of 12 weeks, and follow-up of the patients was done every 4 weeks for a period of 6 months. In patients of group II, oral acitretin 0.5 mg/kg was given plus a wide surgical excision was done. RESULTS AND DISCUSSION: In our study, the commonest site of involvement of hidradenitis suppurativa was axilla in 83.3% patients, perineum was involved in 13.3% patients, and periumbilical involvement was seen in 3.3% patients. The commonest clinical feature was nodules seen in 90% patients; pain was seen in 60% patients, dermal scarring in 73.3% patients, malodorous discharge in 33.3% patients, abscess in 30% patients, and fistulous tracts were seen in 20% patients. The recurrence rate was low (20%) in group II patients in whom oral acitretin was given plus surgical excision was done as compared with group I (40%) in whom oral acitretin was given alone. Medknow Publications & Media Pvt Ltd 2011 /pmc/articles/PMC3276889/ /pubmed/22345763 http://dx.doi.org/10.4103/0019-5154.91821 Text en Copyright: © Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Therapeutic Round
Puri, Neerja
Talwar, Ashutosh
A STUDY ON THE MANAGEMENT OF HIDRADENITIS SUPPURATIVA WITH RETINOIDS AND SURGICAL EXCISION
title A STUDY ON THE MANAGEMENT OF HIDRADENITIS SUPPURATIVA WITH RETINOIDS AND SURGICAL EXCISION
title_full A STUDY ON THE MANAGEMENT OF HIDRADENITIS SUPPURATIVA WITH RETINOIDS AND SURGICAL EXCISION
title_fullStr A STUDY ON THE MANAGEMENT OF HIDRADENITIS SUPPURATIVA WITH RETINOIDS AND SURGICAL EXCISION
title_full_unstemmed A STUDY ON THE MANAGEMENT OF HIDRADENITIS SUPPURATIVA WITH RETINOIDS AND SURGICAL EXCISION
title_short A STUDY ON THE MANAGEMENT OF HIDRADENITIS SUPPURATIVA WITH RETINOIDS AND SURGICAL EXCISION
title_sort study on the management of hidradenitis suppurativa with retinoids and surgical excision
topic Therapeutic Round
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276889/
https://www.ncbi.nlm.nih.gov/pubmed/22345763
http://dx.doi.org/10.4103/0019-5154.91821
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