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CONGENITAL LUPUS ERYTHEMATOSUS

Neonatal lupus erythematosus (NLE) is an autoimmune disease affecting the fetus as a result of transplacental transfer of anti-Ro autoantibodies. Typically, it presents in the first few months of life with an annular form of subacute cutaneous lupus erythematosus. We report an unusual case of NLE pr...

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Autores principales: Bhatt, Taseer Ahmed, Fatani, Hanadi A, Mimesh, Samara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276909/
https://www.ncbi.nlm.nih.gov/pubmed/22345783
http://dx.doi.org/10.4103/0019-5154.91841
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author Bhatt, Taseer Ahmed
Fatani, Hanadi A
Mimesh, Samara
author_facet Bhatt, Taseer Ahmed
Fatani, Hanadi A
Mimesh, Samara
author_sort Bhatt, Taseer Ahmed
collection PubMed
description Neonatal lupus erythematosus (NLE) is an autoimmune disease affecting the fetus as a result of transplacental transfer of anti-Ro autoantibodies. Typically, it presents in the first few months of life with an annular form of subacute cutaneous lupus erythematosus. We report an unusual case of NLE presenting at birth with scaly erythematous telangiectatic patches and macules with skin atrophy involving the face, head, and upper trunk. Thrombocytopenia was discovered on laboratory investigations. Histopathology of skin biopsy was consistent with subacute cutaneous lupus. The mother was clinically free of disease and had no family history of autoimmune disease. Serology (extra-nuclear antigens) was positive in both the baby and the mother. This is a rare presentation of a rare disease.
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spelling pubmed-32769092012-02-16 CONGENITAL LUPUS ERYTHEMATOSUS Bhatt, Taseer Ahmed Fatani, Hanadi A Mimesh, Samara Indian J Dermatol Case Report Neonatal lupus erythematosus (NLE) is an autoimmune disease affecting the fetus as a result of transplacental transfer of anti-Ro autoantibodies. Typically, it presents in the first few months of life with an annular form of subacute cutaneous lupus erythematosus. We report an unusual case of NLE presenting at birth with scaly erythematous telangiectatic patches and macules with skin atrophy involving the face, head, and upper trunk. Thrombocytopenia was discovered on laboratory investigations. Histopathology of skin biopsy was consistent with subacute cutaneous lupus. The mother was clinically free of disease and had no family history of autoimmune disease. Serology (extra-nuclear antigens) was positive in both the baby and the mother. This is a rare presentation of a rare disease. Medknow Publications & Media Pvt Ltd 2011 /pmc/articles/PMC3276909/ /pubmed/22345783 http://dx.doi.org/10.4103/0019-5154.91841 Text en Copyright: © Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Bhatt, Taseer Ahmed
Fatani, Hanadi A
Mimesh, Samara
CONGENITAL LUPUS ERYTHEMATOSUS
title CONGENITAL LUPUS ERYTHEMATOSUS
title_full CONGENITAL LUPUS ERYTHEMATOSUS
title_fullStr CONGENITAL LUPUS ERYTHEMATOSUS
title_full_unstemmed CONGENITAL LUPUS ERYTHEMATOSUS
title_short CONGENITAL LUPUS ERYTHEMATOSUS
title_sort congenital lupus erythematosus
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276909/
https://www.ncbi.nlm.nih.gov/pubmed/22345783
http://dx.doi.org/10.4103/0019-5154.91841
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AT mimeshsamara congenitallupuserythematosus