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Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK
First identified as histone-modifying proteins, lysine acetyltranferases (KATs) and deacetylases (KDACs) antagonize each other through modification of the side chains of lysine residues in histone proteins(1). (De)acetylation of many non-histone proteins involved in chromatin, metabolism or cytoskel...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277212/ https://www.ncbi.nlm.nih.gov/pubmed/22318606 http://dx.doi.org/10.1038/nature10804 |