Functional dissection of lysine deacetylases reveals that HDAC1 and p300 regulate AMPK

First identified as histone-modifying proteins, lysine acetyltranferases (KATs) and deacetylases (KDACs) antagonize each other through modification of the side chains of lysine residues in histone proteins(1). (De)acetylation of many non-histone proteins involved in chromatin, metabolism or cytoskel...

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Detalles Bibliográficos
Autores principales: Lin, Yu-yi, Kiihl, Samara, Suhail, Yasir, Liu, Shang-Yun, Chou, Yi-hsuan, Kuang, Zheng, Lu, Jin-ying, Ni Khor, Chin, Lin, Chi-Long, Bader, Joel S., Irizarry, Rafael, Boeke, Jef D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277212/
https://www.ncbi.nlm.nih.gov/pubmed/22318606
http://dx.doi.org/10.1038/nature10804

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